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Biohaven Leadership Visits Ragon Institute

Mar 17, 2025 Features

Earlier this month, the Ragon Institute welcomed leadership from Biohaven for an insightful visit and discussion with our team. Biohaven CEO Vlad Coric, MD, and board member John Childs toured the Institute and met with Bruce Walker, MD, the Ragon Institute’s founding director, to explore mutual interests and opportunities in the fields of immunology, infectious […]

Ragon Institute Launches Scientific Editing Platform

Mar 14, 2025 Features

The Ragon Institute is pleased to announce the launch of our internal Scientific Editing Platform. Created with the support of the scientific director Facundo Batista, PhD, the platform aims to assist our research community in developing impactful and compelling grant applications. The platform provides scientific editing to enhance our Institute’s grant submissions. The services are […]

New Study Reveals How Regulatory T Cells Prevent Autoimmune Attacks Without Weakening Immunity

Feb 27, 2025 Research Highlights

A new study published in Science by researchers from the Ragon Institute, NIH/NIAID, and the University of Chicago reveals a critical function of the immune system: how regulatory T cells (Tregs) selectively suppress autoimmune reactions while allowing protective responses against infections. The immune system must constantly balance two opposing forces—attacking harmful invaders while preventing damage to healthy […]

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Yu to Speak at IAS 2025: Advancing HIV Science on the Global Stage

Feb 13, 2025 Features

Xu Yu, MD, a faculty member at the Ragon Institute of Mass General Brigham, MIT, and Harvard, and Harvard Medical School, has been selected as a Featured Speaker at IAS 2025, the 13th IAS Conference on HIV Science.  This prestigious international event, taking place from July 13–17 in Kigali, Rwanda, brings together leading HIV scientists […]

DeKosky Honored with AAI ASPIRE Award for Excellence in Immunology Research

Feb 11, 2025 Awards

The Ragon Institute is proud to announce that faculty member and Early Independence Fellow Brandon DeKosky, PhD, has been awarded a prestigious AAI ASPIRE Award by the American Association of Immunologists (AAI). This award recognizes outstanding early-career investigators who have made significant contributions to immunology research and demonstrate exceptional promise in the field. The AAI […]

Leveraging Artificial Intelligence for Vaccine Development: A Ragon-MIT Advancement in T cell Epitope Prediction

Jan 29, 2025 Research Highlights

An exciting collaboration between the Ragon Institute and the Jameel Clinic at MIT has achieved a significant milestone in leveraging artificial intelligence (AI) to aid the development of T cell vaccine candidates. Ragon faculty member Gaurav Gaiha, MD, DPhil, and MIT Professor Regina Barzilay, PhD, AI lead of the Jameel Clinic for AI and Health, […]

Shalek Co-Authors Nature Immunology Study on Nasal Immunity and SARS-CoV-2 Variants

Jan 27, 2025 Research Highlights

A recent study published in Nature Immunology, co-authored by Ragon Institute faculty member Alex K. Shalek, PhD, provides critical insights into how SARS-CoV-2 variants and vaccination status shape immune responses in the nasal mucosa. This research, which utilized advanced single-cell RNA sequencing (scRNA-seq) approaches, explores how cellular responses in the human nasal cavity differ across […]

Amy Barczak Awarded CFD Excellence in Mentoring Award

Jan 13, 2025 Awards

We are delighted to celebrate Ragon faculty Amy Barczak, MD , for receiving the CFD Excellence in Mentoring Ally for Women Faculty Award! This prestigious recognition, presented by the MGH Center for Faculty Development, honors her extraordinary commitment to supporting and advancing women faculty. Amy’s dedication to mentorship is evident in her tireless efforts to […]

HHMI News —Witness to a Pandemic: Bruce D. Walker

Dec 26, 2024 Features

Bruce Walker, MD, the founding director of the Ragon Institute, has dedicated his career to advancing our understanding of HIV and harnessing the immune system to combat infectious diseases. His impactful work has shaped the field of immunology and global health, and his leadership continues to drive scientific innovation. In a compelling profile by the […]

Governor Maura Healey Signs Mass Leads Act at Ragon Institute

Dec 10, 2024 Features

This morning, the Ragon Institute had the privilege of hosting Governor Maura Healey and Lieutenant Governor Kim Driscoll for the ceremonial signing of the Mass Leads Act (H.5100). This landmark legislation is designed to solidify Massachusetts’ position as a global leader in emerging industries like climatetech, applied artificial intelligence (AI), and life sciences while promoting […]

Ringel Lab Study Reveals Age-Related Decline in Tumor-Fighting T Cells and Its Impact on Cancer Treatment

Oct 1, 2024 Research Highlights

Researchers at the Ragon Institute of Mass General Brigham, MIT, and Harvard have uncovered critical insights into how aging impairs the immune system’s ability to fight cancer. A study led by the Ringel Lab at the Ragon Institute and published in Cancer Immunology Research shows that as the body ages a type of immune cells called CD8+ T cells, essential for […]

New Research from the Ragon and Broad Unveils the Protective Role of CD4+ T Cells in Tuberculosis Reinfection

Sep 24, 2024 Research Highlights

Researchers from the Shalek Lab at the Ragon Institute of Mass General Brigham, MIT, and Harvard, in collaboration with the Broad Institute, have uncovered key insights into how prior Mycobacterium tuberculosis (Mtb) infection primes the immune system for enhanced protection against reinfection. This study, published in Immunity on August 30, used a non-human primate model to demonstrate that […]

Todd Allen

Sep 17, 2024 Features

We are deeply saddened to announce the passing of Ragon Institute faculty member Todd M. Allen, PhD, a pioneering researcher in T cell immunotherapy and HIV evolution and transmission. His groundbreaking work on HIV cure research has left an indelible mark on the field and has been an inspiration to many. In addition to his position at the Ragon, […]

New HIV Vaccine Design Shows Promise in Creating Protective Antibodies

Sep 3, 2024 Features

Researchers at the University of Amsterdam, in collaboration with the Batista Lab at the Ragon Institute, have developed a potential new approach for an HIV vaccine. The study, published in Science Immunology, focuses on creating a vaccine component that can stimulate the immune system to produce powerful antibodies against HIV. Titled “Germline-targeting HIV vaccination induces neutralizing antibodies to the CD4 […]

Groundbreaking Study on Lymph Node Excision Advances HIV Cure Research

Aug 28, 2024 Features

Researchers at the Ndhlovu Lab, part of the Ragon Institute and the Africa Health Research Institute (AHRI), have completed a significant study on the safety and practicality of lymph node excisions for HIV cure research in South Africa. The study — led by Ragon faculty member Zaza Ndhlovu, PhD, and published in Frontiers in Immunology — provides […]

“A Two-Way Opportunity” — An Interview with Youry Kim, A Visiting Doherty Institute Exchange Fellow from Australia

Aug 20, 2024 Features

Kim discusses her journey to the Ragon Institute and her aspirations for the future Exchange programs and global collaboration play a vital role in advancing scientific research, allowing researchers to share knowledge, resources, and expertise across borders — a philosophy the Ragon Institute is deeply committed to. For Youry Kim, PhD, the Ragon offered an […]