Ragon Institute
Oct 26, 2022
Congratulations to Dr. Brandon DeKosky, the 2022 James S. Huston Antibody Science Talent Award recipient! This award is given annually by The Antibody Society to an early career researcher who has made important contributions to antibody science. DeKosky and his lab have developed a suite of high-throughput single-cell platforms for large-scale analyses of adaptive immunity. Key […]
Oct 20, 2022
National Hispanic Heritage Month is September 15–October 15. This month commemorates the history, achievements, and contributions of Hispanic people from or connected with Spanish-speaking regions, including those whose ancestors came from Spain, Mexico, and much of the Caribbean and Central and South America. During this month we spoke with Wilfredo Garcia-Beltran, MD, PhD, a clinician-scientist […]
Oct 7, 2022
National Hispanic Heritage Month is September 15–October 15. This month commemorates the history, achievements, and contributions of Hispanic people from or connected with Spanish-speaking regions, including those whose ancestors came from Spain, Mexico, and much of the Caribbean and Central and South America. Our next Q&A interviewee is Franklin Lora, Supply Support Associate and Day […]
Oct 6, 2022
National Hispanic Heritage Month is September 15–October 15. This month commemorates the history, achievements, and contributions of Hispanic people from or connected with Spanish-speaking regions, including those whose ancestors came from Spain, Mexico, and much of the Caribbean and Central and South America. Our next Hispanic Heritage Q&A is with Suzanne Carpe Elías, a research […]
Sep 30, 2022
National Hispanic Heritage Month is September 15–October 15. This month commemorates the history, achievements, and contributions of Hispanic people from or connected with Spanish-speaking regions, including those whose ancestors came from Spain, Mexico, and much of the Caribbean and Central and South America. For our Q&A interview series, we spoke with Thor Sandstad, Senior Facilities […]
Sep 29, 2022
Key Takeaways Researchers compared protein- and mRNA-based HIV immunogens in mice. mRNA-based immunization significantly increased activation and recruitment of broadly neutralizing antibody (bnAb) precursors. BOSTON – The development of a durable and effective HIV vaccine is still elusive after almost forty years of research, but a new study testing a germline-targeting vaccination strategy provides insights […]
Sep 28, 2022
During September 15–October 15, we commemorate the history, achievements, and contributions of Latin people from or connected with Spanish-speaking regions, including those whose ancestors came from Spain, the Caribbean, North, Central, and South America. Next up in our Latine Q&A interview series with Ragon employees is Emily Marte, a veterinary technician in Todd Allen’s lab. […]
Sep 26, 2022
Photo provided by Andrea Garavito National Hispanic Heritage Month is September 15–October 15. This month commemorates the history, achievements, and contributions of people from or connected with Spanish-speaking regions, including those whose ancestors came from Spain, Mexico, and much of the Caribbean and Central and South America. To celebrate Hispanic Heritage, we’re publishing a series […]
Sep 20, 2022
Last month, a team of instructors from the U.S. and South Africa led a five-day workshop at Nelson Mandela School of Medicine, University of KwaZulu-Natal (UKZN) in Durban, South Africa. The objective of the course was to build research data analysis capacity for sub-Saharan African researchers by teaching R programming language basics and data modeling […]
Aug 31, 2022
Key Takeaways Researchers used single-cell RNA-sequencing to study small intestinal biopsies of 33 individuals with environmental enteropathy (EE), which is thought to be a major contributor to malnutrition. They identified potential cellular and molecular targets for treatment. BOSTON – Environmental enteropathy (EE), or gut inflammation due to environmental factors, is thought to be a major […]
Aug 17, 2022
Key Takeaways Antibodies elicited by a first vaccination in HIV and SARS-CoV mouse models shape the antibody response to later vaccination. This research elucidates the basic biology of the antibody response, which may inform future vaccine development. BOSTON – The human immune system is a library of responses to past exposures. In a new study […]
Aug 10, 2022
Key Takeaways A single genetic variant on human B cell receptors is responsible for differences in immune response to an experimental universal flu vaccine that targets the influenza viral spike protein. Findings suggest some people may not have broadly neutralizing antibody responses to universal flu vaccines, but there is the potential to rescue immune response. […]
Aug 3, 2022
The Ragon’s Biosafety Level 3 lab plays a key role in translational studies of emerging viral infections When scientists want to study potentially dangerous pathogens—bacteria, viruses, or other organisms that can cause disease—they need to use specialized laboratory spaces. At the Ragon Institute, our state-of-the-art Biosafety Level 3 (BSL-3) laboratory is where experiments can be […]
Jul 27, 2022
Key Takeaways Researchers investigated the efficacy of four naturally occurring IgG subclasses against vaginal HIV infection. In a humanized mouse model, the antibody VRC07 IgG2 showed substantially reduced protection relative to other IgG subclasses. BOSTON – Immunoglobulin gamma (IgG) antibodies are produced by the immune system after exposure to HIV. There are four different types […]
Jun 28, 2022
BOSTON – Although pregnant individuals and newborns may face elevated risks of developing more severe cases of COVID-19 following SARS-CoV-2 infection, data indicate that COVID-19 vaccination during pregnancy can help to protect both the mother and child. New research collaboratively led by investigators at Massachusetts General Hospital (MGH) and Brigham and Women’s Hospital (BWH) and published […]
Jun 21, 2022
Sikhulile Moyo discusses the benefits of international collaboration and a culture of transparency Last week, the Ragon Institute welcomed virologist Sikhulile Moyo, PhD, laboratory director of the Botswana-Harvard AIDS Institute Partnership (BHP) and research associate at Harvard T.H. Chan School of Public Health, for a visit. Moyo is a collaborator with Ragon members Mathias Lichterfeld, […]