Research Highlights
New Study Reveals How Regulatory T Cells Prevent Autoimmune Attacks Without Weakening Immunity
Feb 27, 2025 Research Highlights
A new study published in Science by researchers from the Ragon Institute, NIH/NIAID, and the University of Chicago reveals a critical function of the immune system: how regulatory T cells (Tregs) selectively suppress autoimmune reactions while allowing protective responses against infections. The immune system must constantly balance two opposing forces—attacking harmful invaders while preventing damage to healthy […]
Leveraging Artificial Intelligence for Vaccine Development: A Ragon-MIT Advancement in T cell Epitope Prediction
Jan 29, 2025 Research Highlights
An exciting collaboration between the Ragon Institute and the Jameel Clinic at MIT has achieved a significant milestone in leveraging artificial intelligence (AI) to aid the development of T cell vaccine candidates. Ragon faculty member Gaurav Gaiha, MD, DPhil, and MIT Professor Regina Barzilay, PhD, AI lead of the Jameel Clinic for AI and Health, […]
New HIV Vaccine Design Shows Promise in Creating Protective Antibodies
Sep 3, 2024 Features
Researchers at the University of Amsterdam, in collaboration with the Batista Lab at the Ragon Institute, have developed a potential new approach for an HIV vaccine. The study, published in Science Immunology, focuses on creating a vaccine component that can stimulate the immune system to produce powerful antibodies against HIV. Titled “Germline-targeting HIV vaccination induces neutralizing antibodies to the CD4 […]
Alex Shalek Appointed Director of IMES at MIT
Jul 30, 2024 Features
We are thrilled to announce that Ragon faculty member Alex Shalek, PhD, has been appointed as the new Director of the Institute for Medical Engineering and Science (IMES) at MIT, effective August 1, 2024. Shalek joined the Ragon Institute a decade ago, playing a pivotal role in advancing our mission. His innovative work spans genomics, […]
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Program for Immunophysiology and Disease
Revealing mechanisms of immune control and disease pathogenesis to prepare for and protect against future global health threats.
Program for Patient Focused Immunology
Bringing observations from the bedside to the bench and back, worldwide.