Galit Alter

Galit Alter, PhD

Principal Investigator


Member

Ragon Institute of MGH, MIT and Harvard

Professor of Medicine

Harvard Medical School

Co-Director

Harvard University Center for AIDS Research (CFAR)

Contact


(857) 268-7003

400TS 784

TikTok

Systems Serology

Research Overview

The Alter lab focuses on the development of biological tools to determine individual antibody responses to a number of infectious diseases, such as HIV, Ebola virus, Mycobacterium tuberculosis, malaria, and SARS-CoV-2. This approached, deemed Systems Serology, allows us to understand what specific antibody features track with favorable patient outcomes as they battle infection with these diseases.

The Alter lab develops and uses systems biology tools to define the correlates of immunity against infectious diseases that ravage the globe. To this end, we developed a novel, ever-evolving approach to probing humoral immunity that she termed ‘systems serology’. We use this novel -omics platform to profile the remarkable diversity of antibodies generated in response to pathogens or vaccines and their abilities to leverage the immune system to fight disease. Our group interrogates antibody profiles, using machine learning and other high dimensional tools to define the specific antibody profiles/features that track with favorable patient outcomes in diseases such as HIV, Ebola virus, Mycobacterium tuberculosis, malaria, and SARS-CoV-2.

Recognition and Media

Dr. Alter has received the MGH Research Scholar Award and Financial Support and Glycobiology Significant Achievement Award (2018). Her lab has also received significant support for their SARS-CoV-2 work.

About

Dr. Alter was born in Israel and raised in Canada, and graduated and completed PhD training in Experimental Medicine at McGill University. She then completed her postdoctoral training at the Massachusetts General Hospital, where she became an Instructor in 2008.

Lab Team

Caroline Atyeo

Graduate Student

Biana Bernshtein

Research Fellow

Carolyn Boudreau

Graduate Student

Deniz Cizmeci

Research Fellow

Leela Davies

Research Fellow

Brandon Davis

Senior Research Technologist

Christine Davis

Graduate Student

Elizabeth DeRiso

Research Fellow

Jonathan Fallon

Research Specialist

Brooke Fenderson

Research Technician I

Stephanie Fischinger

Graduate Research Assistant

Laura Fontana

Program Manager

Daritza Germosen

Research Technician I

Matthew Gorman

Research Fellow

Patricia Grace

Research Fellow

Wenyue (Judy) Guo

Senior Research Technologist

Jonathan Herman

Researcher

Jeff Hsiao

Graduate Student

Edward Irvine

Graduate Student

Anita Iyer

Research Fellow

Jessica Lee

Research Technician I

Wonyeong Jung

Research Fellow

Jaewon Kang

Research Technician I

Paulina Kaplonek

Research Fellow

Wiktor Karpinski

Research Technician I

Ryan MacVicar

Research Technician I

Jenny Maron

Graduate Student

Shreya Nair

Undergraduate Student

Nadege Nziza

Research Fellow

Krista Pullen

Graduate Student

Vicky Roy

Research Specialist

Sally Shin

Research Technician II

Sameed Siddiqui

Graduate Student

Marianna Spatola

Research Fellow

Daniel Stein

Undergraduate Student

Xin Tong

Research Fellow

Nicholas Webb

Research Fellow

Menbere Wolde

Researcher

Dansu Yuan

Research Technician I

Daniel Zhu

Graduate Student

Tomer Zohar

Graduate Student

Yonathan Zur

Research Technician I

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