Ragon Institute
Sep 22, 2025 Features
A new Cell Reports study from the Ndhlovu Lab with partners in South Africa and Malawi explains how HIV survives in lymph nodes during treatment. The team shows that the virus weakens nearby “killer” CD8 T cells right where HIV concentrates most, inside B cell follicles. Researchers examined lymph node tissue from people with and […]
Sep 17, 2025 Features
A new multi-center study led by investigators at the Yu Lab reports that biological sex influences how the body “selects” long-lived HIV reservoir cells during years of effective antiretroviral therapy. The team finds stronger innate immune pressure in females, offering fresh clues for cure-directed strategies. Published in Science Translational Medicine, the study analyzed more than 4,000 […]
Sep 11, 2025 Features
A new study led by investigators at the Kwon Lab and collaborators shows how energy use by gut immune cells can weaken the intestinal lining in people living with HIV, even when the virus is controlled by treatment. The work identifies a metabolic switch inside these cells as a promising target to help protect the […]
Sep 8, 2025 Features
The Ragon Institute is deeply saddened by the passing of David Baltimore, PhD, a Nobel laureate in physiology or medicine who served as a co-chair of our Scientific Advisory Board for many years and helped to set the scientific direction of our institutional research. “The passing of David Baltimore, Nobel Laureate, is a seismic loss […]
Sep 2, 2025 Awards
The Ragon Institute congratulates Anika Hutton of the Moura-Silva Lab on her selection to the 2025 cohort of the Howard Hughes Medical Institute (HHMI) Gilliam Fellows Program. Hutton, a PhD student advised by Hernandez Moura Silva, joins a national community of emerging scientists committed to impactful research and inclusive training environments. The Gilliam Fellows Program […]
Aug 27, 2025 Features
In July 2024, we published a story with the headline: “One of the 7 people cured of HIV tells his story. Can his cure work for others.” This summer, at the International AIDS Society conference, came news of an exciting new development in the the ongoing effort to bring the epidemic to an end. This story is […]
Aug 21, 2025 Features
We are excited to announce that Eric Dang, PhD, will be joining the Ragon Institute as a new faculty member, where he will lead the Dang Lab. Eric will serve as a Core Member of the Ragon Institute and also hold an appointment as an Assistant Professor of Immunology at Harvard Medical School. Dang received […]
Aug 18, 2025 Features
The Ragon Institute congratulates faculty member Harikesh Wong, PhD, Core Member at the Ragon and an Assistant Professor in the MIT Department of Biology, on receiving the National Science Foundation’s Faculty Early Career Development (CAREER) Award — the NSF’s most prestigious honor for early-career faculty. The CAREER Award recognizes teacher-scholars who excel in integrating research […]
Aug 4, 2025 Research Highlights
Led by a team of African researchers, first doses of the novel T cell-inducing GRAdHIVNE1 vaccine candidate have been given. Harare, Zimbabwe; Rome, Italy; New York, NY, and Cambridge, MA, USA — August 4, 2025 — The Mutala Trust, ReiThera Srl (ReiThera), the Ragon Institute of Mass General Brigham, MIT, and Harvard (the Ragon Institute), […]
Jul 31, 2025 Features
The Ragon Institute is pleased to announce that Eric Sun, PhD, will join the institute’s faculty and establish the Sun Lab, dedicated to advancing computational science and deepening our understanding of the biology of aging. Sun will hold dual appointments as a Member of the Ragon Institute and an Assistant Professor in MIT’s Department of […]
Jul 23, 2025 Features
A recent study from the Ndhlovu Lab at the Ragon Institute has uncovered significant gaps in global vaccine strategies, revealing that immune system gene diversity in African populations has been widely overlooked in current vaccine design approaches. The study, published in Scientific Reports, investigated high-resolution data on Human Leukocyte Antigen (HLA) genes in populations from […]
Jul 11, 2025 Features
Baquero discusses her HIV research, her time at the Ragon Institute, and the importance of preserving scientific and public health progress in Argentina. Lucia Baquero is a visiting doctoral candidate from Buenos Aires, Argentina, currently conducting research at the Ragon Institute as part of her doctoral work. She’s part of a longstanding collaboration between her […]
Jun 24, 2025 Features
Tomer Milo, PhD, a postdoctoral fellow in the Wong Lab at the Ragon Institute of Mass General Brigham, MIT, and Harvard, has received the esteemed Jane Coffin Childs Fellowship. The fellowship supports promising early-career scientists conducting innovative biomedical research. Milo, who completed his doctoral work at the Weizmann Institute of Science, is recognized for his […]
Jun 11, 2025 Features
In 2022, the Mark and Lisa Schwartz AI/ML Initiative was launched at the Ragon Institute to explore the boundaries of artificial intelligence and machine learning within the context of immunology. Its first major project was the development of the MUNIS epitope predictor by the Gaiha Lab in collaboration with MIT. Now, Ragon faculty member Sophia […]
May 30, 2025 Features
Researchers at the Ragon Institute have made a significant discovery about how antibodies can directly enhance the body’s ability to fight Mycobacterium tuberculosis (Mtb), the bacteria responsible for tuberculosis (TB). Despite decades of research, TB remains one of the deadliest infectious diseases worldwide, with about 10 million new cases and 1.6 million deaths annually. Currently, […]
May 16, 2025 Features
The Ragon Institute is proud to announce that Gaurav Gaiha, MD, DPhil, has been awarded the prestigious HST Seidman Prize for MD Research Mentorship. Presented annually by the Harvard-MIT Health Sciences and Technology (HST) program, this award recognizes a faculty member for their outstanding research mentorship of an HST MD student. Established in 2009 by […]
May 8, 2025 Features
The Ragon is proud to recognize graduate students and alumni Anusha Nathan of the Gaiha Lab and Leonard Nettey of the Shalek Lab, who have each been honored with the prestigious Jeffrey Modell Prize. The ceremony presenting the award was held April 30 on the Harvard campus. This award, conferred jointly by the Jeffrey Modell […]
May 6, 2025 Features
To understand what drives disease progression in tissues, scientists need more than just a snapshot of cells in isolation — they need to see where the cells are, how they interact, and how that spatial organization shifts across disease states. A new computational method called MESA (Multiomics and Ecological Spatial Analysis), detailed in a study […]
Apr 24, 2025 Features
A recent study published in Science Translational Medicine, co-authored by Ragon Institute faculty members Azza Idris, MD, PhD, and Galit Alter, PhD, demonstrates that engineering antibodies to enhance Fc receptor binding can significantly improve their effectiveness against malaria infection. The researchers tested modified versions of human monoclonal antibodies, CIS43LS and L9LS, which target a protein […]