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Germline-encoded affinity for cognate antigen enables vaccine-amplification of a human broadly neutralizing response against influenza virus

Sep 27, 2019

Article originally published on Cell Press, Immunity, September 25, 2019 DOI:https://doi.org/10.1016/j.immuni.2019.09.001 Cambridge, MA. A team of researchers led by Dr. Daniel Lingwood from the Ragon Institute of Mass General, MIT, and Harvard have investigated how Human broadly neutralizing antibodies (bnAbs) against influenza virus can be biased for VHgene usage, suggesting gene-encoded development pathways. Sangesland et […]

Identification Of A Direct Interaction Between NK Cells And A Subset Of HLA Class II Molecules

Aug 5, 2019

News from the HPI Monday, 29. July 2019 Hamburg. A scientific team from the Research Department of Virus Immunology at the Heinrich Pette Institute, Leibniz Institute for Experimental Virology (HPI) has investigated the binding of NK cell receptors to HLA class II molecules. The results have now been published in the renowned journal “Nature Immunology”. […]

Studies show early detection, prompt ARV treatment provide hope for the elimination of HIV

Jul 17, 2019

Could early treatment with antiretroviral (ARV) therapy help the body fight off HIV? Researchers affiliated with the Sub-Saharan African Network for TB/HIV Research Excellence (SANTHE) are convinced that early ARV therapy is critical to the treatment of HIV.   Researchers at the University of KwaZulu-Natal (UKZN) in Durban, South Africa are conducting studies they believe […]

New vaccine strategy boosts T-cell therapy

Jul 11, 2019

Super-charging a treatment for leukemia also makes it effective on solid tumors. Anne Trafton | MIT News Office A promising new way to treat some types of cancer is to program the patient’s own T cells to destroy the cancerous cells. This approach, termed CAR-T cell therapy, is now used to combat some types of […]

Eight Harvard students travel to KZN for a unique HIV research internship

Jul 1, 2019

Some of the world’s brightest young health minds will be working under the supervision of senior HIV scientists to gain insight into combating this global epidemic. KWAZULU-NATAL, South Africa — Eight students from Harvard University are currently in KwaZulu-Natal (KZN) for an intensive internship program to learn about the important HIV prevention and cure research […]

Ragon Institute top fundraiser for 34th annual AIDS Walk

Jun 18, 2019

Team Ragon raises $64,014 for crucial services BOSTON, Mass. – On Sunday, June 2nd, 2019, more than 30 Team Ragon members, including Ragon Institute employees and their friends and family, gathered at the DCR Hatch Memorial Shell for the annual Boston AIDS Walk and 5K Run. The AIDS Walk, now in its 34th year, is […]

Breaking the Code: How is a mother’s immunity transferred to her baby?

Jun 13, 2019

Ragon Institute-led study identifies factors contributing to placental transfer of antibodies CAMBRIDGE, Mass. – One of the most successful interventions in reducing infectious disease worldwide, vaccination still has limited effectiveness in protecting one group of patients – newborn infants. Now a study based at the Ragon Institute of Mass General, MIT, and Harvard has determined […]

Ragon Institute hosts Neuro-Immune Symposium

May 28, 2019

Two-day symposium brings together experts in the growing field of neuroimmunology On March 28th and 29th, 2019, the Ragon Institute of Mass General, MIT, and Harvard hosted a Neuro-Immune Symposium with the goal of bringing together world-class experts in neuroimmunology and the related fields of neurobiology and immunology to share their cutting-edge research and discoveries, […]

Early antiretroviral treatment may preserve key immune responses to HIV

May 22, 2019

Ragon Institute study findings could pave the way to vaccine development CAMBRIDGE, Mass. – Instituting combination antiretroviral (ART) treatment at the earliest stages of HIV infection may allow the generation of functional CD8 “killer” T cells and preservation of the CD4 helper T cells that are the virus’s primary target.  Investigators from the Ragon Institute […]

5 South African Traditional Healers honored in the USA

May 16, 2019 Features

Five Traditional Healers from KwaZulu-Natal – who are central to an innovative program run in partnership with a local South African NGO and the KZN Department of Health – traveled to Cambridge, Massachusetts, where they were hosted for five days and honored for their work by the prestigious Ragon Institute of Mass General, MIT, and […]

Ragon Institute study identifies viral peptides critical to natural HIV control

May 2, 2019 Features

T-cell targeting of essential amino acids may underlie spontaneous HIV suppression, define path to a vaccine CAMBRIDGE, Mass. – Investigators at the Ragon Institute of Mass General, MIT, and Harvard have used a novel approach to identify specific amino acids in the protein structure of HIV that appear critical to the ability of the virus […]

MGH receives $200 million to advance research into complex diseases

May 2, 2019

Largest gift in hospital history will bolster the Ragon Institute of Mass General, MIT, and Harvard BOSTON – Massachusetts General Hospital (MGH) announced it has received the largest gift in the hospital’s history – $200 million – to endow the Ragon Institute of Mass General, MIT, and Harvard. This landmark contribution from philanthropists and longtime […]

Announcement of Record Gift to MGH to Endow the Ragon Institute

Apr 26, 2019

We are thrilled to let you know that the MGH has received the largest philanthropic gift in its history – a $200 million contribution to support the Ragon Institute of Mass General, MIT, and Harvard. This extraordinary gift comes from Phillip (Terry) and Susan Ragon, long-time supporters of the hospital, whose transformational contribution will ensure […]

Biostatistics Course Strengthens Statistics Skills in Research Community

Apr 3, 2019

The availability of a variety of free, user-friendly statistical software packages has enabled many scientists to perform their own analyses and generate results without a formal knowledge of programming languages. This democratization of data science can be hugely important to researchers wishing to analyze and interpret their research data, but can be risky without sufficient […]