Favicon
Favicon

Ragon faculty sheds light on intricate functions of Resident Tissue Macrophages (RTM’s) which extend beyond immune defense

Date: April 15, 2024 By: Nick Kolev

The lab of the Ragon Institute faculty member Hernandez Moura Silva, PhD, recently published a review in Science Immunology regarding resident tissue macrophages (RTMs), shedding light on their multifaceted roles in organ health. 

RTMs, integral components found abundantly across various organs, have traditionally been recognized for their immune defense functions. However, this review highlights their contributions extend far beyond immune response.

The manuscript explores the specialized activities of RTMs tailored to sustain critical homeostatic functions within organs. It explored how the distinct microenvironments of different organs influence the development and functions of RTMs and discusses the implications of dysregulation, which can lead to various diseases. 

Furthermore, the manuscript underscores the importance of recognizing both the commonalities and unique characteristics among RTM subsets across different organs, aiming to consolidate recent classifications into a cohesive understanding of their roles in maintaining tissue homeostasis.

More News

Ragon Postdoc Awarded Prestigious NIH K99 Pathway to Independence Award

The Ragon Institute is proud to recognize Upasana Das Adhikari, PhD, a postdoctoral fellow in the Kwon Lab, who has been awarded the prestigious K99 Pathway to Independence Award by the National Institutes of Health (NIH)

“Future African Scientist” — The Unlikely Friendship Teaching the Next Generation of African Researchers

In January 2020, two students from across the world met on the “Evolution of an Epidemic” course. Their friendship inspired the creation of a program they hope will benefit African science for years to come.

Ragon Partnering with Bright Horizons to Offer Child Care Center at New Headquarters

The Ragon Institute is delighted to announce the upcoming launch of the Ragon Child Care Center at our new building at 600 Main Street. Operated by our renowned partners at Bright Horizons, the Ragon Child Care Center will offer top-notch early childhood education and care right at the heart of our community.