Principal Investigator
Core Member
Ragon Institute of Mass General, MIT, and Harvard
Associate Professor in Microbiology
Harvard Medical School
Assistant in Immunology
Massachusetts General Hospital
857.268.7118
Office #954
Our research focuses on the development of adaptive immune responses, protein evolution and the interactions between host and pathogen using a combination of biophysical, biochemical and molecular virology techniques.
We are structural biologists who bring mechanistic and quantitative approaches to address fundamental problems in virology and immunology. We primarily study orthomyxo- and flaviviruses but our interests extend to emerging viruses (e.g. alpha-, arena-, bunya- and filoviruses) and other pathogens. We are strong believers in collaboration and are always open to pursuing new directions and pathogens!
Dr. Schmidt received undergraduate degrees in biology and chemistry from Emmanuel College and a PhD in virology from Harvard University with Stephen C. Harrison. Postdoctoral training was done at Harvard Medical School and Boston Children’s Hospital, also with Stephen C. Harrison.
Schmidt AG, Xu H, Khan AR, O’Donnell T, Khurana S, King LR, Manischewitz J, Golding H, P. Suphaphiphat P,CarfiA, Settembre EC, Dormitzer PR, Kepler TB, Zhang R-J, Moody MA, Haynes BF, Liao HX, Shaw DE and Harrison SC.
PNAS 110, 2013. (1) 264-269
Schmidt AG, Therkelsen MD, Stewart S, Moody MA, Haynes BF, Liao HX, Harrison SC
Cell, 2015. 161, 1026-1034. PMCID: PMC4441819
Schmidt AG, Khoi KT, McCarthy KR, Kepler TB, Liao HX, Moody MA, Haynes BF and Harrison SC
Cell Reports, 2015. 13 2842-50
McCarthy, KR, Raymond, DD, Do, K.T., Schmidt, AG, Harrison, SC.
PNAS, 2019 116 (52): 26745-51
Bajic G, Maron MJ, Adachi Y, Onodera T, McCarthy KR, McGee CE, Sempowski GD, Takahashi Y, Kelsoe G, Kuraoka M, Schmidt AG.
Cell Host Microbe, 2019. 12;25(6):827-835. PMCID: PMC6748655
Bajic G, Maron MJ, Caradonna TM, Tian M, Mermelstein A, Fera D, Kelsoe G, Kuraoka M, Schmidt AG.
ACS Infect Dis. 2020 May 8;6(5):1182-1191. doi: 10.1021/acsinfecdis.0c00008. Epub 2020 Apr 20. PubMed PMID: 32267676
Timothy Caradonna
Graduate Student
Agnes Cheng
Research Technician I
Jared Feldman
Graduate Student
Emerson Glassey
Research Fellow
Blake Hauser
Graduate Student
Rochel Hecht
Catherine Jacob-Dolan
Graduate Student
Ty Kannegieter
Research Laboratory Assistant
Gabrielle Law
Graduate Student
Daniel Maurer
Graduate Student
Anne Roffler
Graduate Research Assistant
Estefania Reyes Sepulveda
Graduate Student
Dana Thornlow
Research Fellow
Mya Vu
Graduate Research Assistant
Ian Windsor
Postdoctoral Fellow
Our people are our greatest asset. We are committed to creating a supportive and inclusive environment that is welcoming for all.
The Ragon’s faculty includes many of the world’s most creative scientists, engineers, and clinicians.
The Ragon’s research creates knowledge from our collaborative, cross-disciplinary approach, breaking down the silos of academia.