Ragon Institute

Liu Lab

Building tools to characterize spatial and temporal immune cell interactions

Lab Overview

The Liu lab builds tools to ask new biological questions, in particular for characterizing spatial and temporal dynamics of immune cells in tissues. We aim to study immune cell interactions in tissues, the dynamics across immune development and aging, and T and B cell repertoires in situ.

We investigate the dynamic changes that occur in the immune system across different stages of life. We are dedicated to unraveling the complexities of the immune system’s behavior and its critical role in maintaining tissue homeostasis and responding to pathological challenges. By investigating healthy and disease states, we aim to shed light on the processes leading to immune-mediated tissue damage and identify potential therapeutic targets. Recent projects have explored immunological aging of T and B cells, repertoires in cancer and infectious disease contexts, and methods for measuring long-timescale interactions.

Lab Website

Sophia Liu, PhD

Principal Investigator

Affiliation

  • Core Member and Early Independence Fellow, Ragon Institute of Mass General, MIT, and Harvard

About

Dr. Sophia Liu received her PhD in Biophysics from Harvard University, supported by the NSF Graduate Fellowship, and is affiliated with the Harvard-MIT Health Sciences and Technology Medical Engineering and Medical Physics Program. She received her BS in Chemical-Biological Engineering from MIT. Through BroadIgnite, she also serves as a Principal Investigator at the Broad Institute of MIT and Harvard.

Related Research Foci

  • Artificial Intelligence and Machine Learning
  • Cancer Immunology
  • Human Immunogenetics
  • Fundamental Immunology
  • Infectious Disease Pathogenesis
  • Computational Science
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Related Areas of Study

  • Aging
  • Autoimmune
  • Cancer
  • HIV
  • Infectious Disease
View All +

Looking for Collaboration?

Contact Us

Lab Team

Ally Vernich

Research Technician

Kaitlyn Zhang

Undergraduate Researcher

Kenneth Wei

Graduate Student

Kevin Chen

Research Technician

Larissa Ma

Undergraduate Researcher

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