Ragon Institute

Ghebremichael Lab

Application and development of statistical methods

Lab Overview

The Ghebremichael Lab specializes in the application and development of statistical methods, including data management, data analysis and more, for HIV/AIDS, TB, and immunologic research. We are dedicated to ensuring that studies are well-designed, correctly analyzed, clearly presented, and correctly interpreted.

We provide expertise in the planning, conduct and analysis of research with the goal of enhancing the scientific quality of research at the institute. We also provide training in software use, statistical analysis and other quantitative tools for members of the Ragon Institute. The training, given in either a course or a one-on-one meeting, includes education on statistical methods and software, such as SAS, R, and MATLAB.

Lab WebsiteHarvard Catalyst

Musie Ghebremichael, PhD

Affiliation

  • Harvard School of Medicine, Associate Professor

About

Dr. Ghebremichael is a statistician at the Ragon Institute, an Associate Professor of Medicine at Harvard Medical School, and an Associate Investigator at the MGH Biostatistics Center. He provides statistical support to Ragon and Ragon-affiliated investigators. Dr. Ghebremichael received a bachelor’s degree in mathematics from Asmara University, Eritrea, his PhD in statistics from Rice University, and completed a post-doctoral fellowship at Yale University with a primary research focus was on statistical methods applied to HIV/AIDS research. Before joining the Ragon Institute, he worked as a statistician for Harvard University Center for AIDS Research (HU CFAR) and the Dana Farber Cancer Institute.

Related Research Foci

  • Computational Science
  • Artificial Intelligence and Machine Learning
  • FRESH

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Selected Publications

Bivariate Quantile Residual Life Functions for Estimating Immunological and Virological Recovery in HIV Patients.

Ruhul Ali Khan, Musie Ghebremichael

Biometrical Journal, 68(2), e70112

February 28, 2026

Assessing the Performance of Longitudinal T-Lymphocytes as Biomarkers of Immune Recovery in HIV-infected Children with or without TB Co-Infection.

Musie Ghebremichael

Journal of Applied Statistics 2025, 1–16

September 24, 2025

Comparing Estimation Methods for the Area Under the Bi-Weibull ROC Curve.

Ruhul Ali Khan, Musie Ghebremichael

Pharmaceutical Statistics 24,no. 5 (2025): e70038

September 5, 2025

Comparison of the binormal and Lehman receiver operating characteristic curves.

Musie Ghebremichael, Haben Michael

Communications in Statistics-Simulation and Computation. 2022; 1-14

January 1, 2022

A comparison of machine learning techniques for classification of HIV patients with antiretroviral therapy-induced mitochondrial toxicity from those without mitochondrial toxicity

Lee J, Paintsil E, Gopalakrishnan V, Ghebremichael M.

BMC Med Res Methodol. 2019 Nov 27;19(1):216

November 27, 2019

Comparing the Diagnostics Accuracy of CD4+ T-Lymphocyte Count and Percent as a Surrogate Markers of Pediatric HIV Disease

Ghebremichael M, Michael H, Tubbs J, Paintsil E.

J Math Stat. 2019;15(1):55-64

January 1, 2019

The ROC Curve for Cohort Designs

Michael H, Tian L, and Ghebremichael M.

Biostatistics. 2019 Jul 1;20(3):433-451

July 1, 2019

Effect of Tuberculosis on Immune Restoration among HIV-Infected Patients Receiving Antiretroviral Therapy

Ghebremichael M, Habtemicael S.

Journal of Applied Statistics 2018; 45(13). 2357-2364

January 1, 2018

Looking for Collaboration?

(857) 268-7006

[email protected]

600 Main Street, Rm 358

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