Research Highlights
Ndhlovu Lab Study Highlights Crucial Genetic Diversity for Effective Vaccine Development in Africa
Jul 23, 2025 Features
A recent study from the Ndhlovu Lab at the Ragon Institute has uncovered significant gaps in global vaccine strategies, revealing that immune system gene diversity in African populations has been widely overlooked in current vaccine design approaches. The study, published in Scientific Reports, investigated high-resolution data on Human Leukocyte Antigen (HLA) genes in populations from […]
Alter, Idris Joint Study Shows Engineered Antibodies Improve Malaria Protection
Apr 24, 2025 Features
A recent study published in Science Translational Medicine, co-authored by Ragon Institute faculty members Azza Idris, MD, PhD, and Galit Alter, PhD, demonstrates that engineering antibodies to enhance Fc receptor binding can significantly improve their effectiveness against malaria infection. The researchers tested modified versions of human monoclonal antibodies, CIS43LS and L9LS, which target a protein […]
New Study Offers Hope in Reducing HIV Risk for Young Women in South Africa
Apr 4, 2025 Features
A healthy vaginal environment dominated by Lactobacillus crispatus is associated with a lower risk of HIV acquisition among women. However, only a fraction of women worldwide, and even fewer in Africa, have vaginal microbiomes dominated by Lactobacillus crispatus. Now, a groundbreaking study led by Drs. Anke Hemmerling and Craig Cohen from UCSF’s Department of Obstetrics, Gynecology & Reproductive […]
Yu to Speak at IAS 2025: Advancing HIV Science on the Global Stage
Feb 13, 2025 Features
Xu Yu, MD, a faculty member at the Ragon Institute of Mass General Brigham, MIT, and Harvard, and Harvard Medical School, has been selected as a Featured Speaker at IAS 2025, the 13th IAS Conference on HIV Science. This prestigious international event, taking place from July 13–17 in Kigali, Rwanda, brings together leading HIV scientists […]
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Program for Immunophysiology and Disease
Revealing mechanisms of immune control and disease pathogenesis to prepare for and protect against future global health threats.
Program for Immune Engineering
Leveraging discoveries to develop cutting-edge diagnostics and treatments.