Favicon
Favicon

Data Durban 2022: Exploratory Data Analysis & Modeling in R with Microbiome Applications

Date: September 20, 2022 By: Blythe Gulley and Emily Makowski

Last month, a team of instructors from the U.S. and South Africa led a five-day workshop at Nelson Mandela School of Medicine, University of KwaZulu-Natal (UKZN) in Durban, South Africa. The objective of the course was to build research data analysis capacity for sub-Saharan African researchers by teaching R programming language basics and data modeling best practices. It covered UNIX computing, an introduction to R, library prep of human microbiome samples, processing raw microbiome data, and connecting sequencing data and metadata through exploratory data analysis.

Data Durban 2022 was organized by Doug Kwon, MD, PhD, at the Ragon Institute and Harvard Medical School; Joseph Elsherbini, PhD, bioinformatics analyst in the Kwon Lab; Scott Handley, PhD, at University of Washington in St. Louis; and Tulio de Oliveira, PhD, at the University of KwaZulu-Natal.

Fifty trainees from seven countries—Botswana, Cameroon, Democratic Republic of the Congo, Mozambique, Nigeria, South Africa, and Zimbabwe—were accepted into Data Durban 2022, which ran from August 22-26, 2022. The workshop was free to participants and provided breakfast, lunch, tea, and a mid-week networking reception in addition to instruction.

At the end of the workshop, participants left feeling empowered and ready to use R independently for their research and data analysis. “I had trouble learning R on my own. This workshop could not come at a better time. The workshop was successful as I learned far more than just a few basics, but also my confidence in using R has increased,” said one participant in anonymous course feedback.

Funding was generously provided by the Sub-Saharan African Network for TB/HIV Research Excellence (SANTHE) and the Harvard University Center for AIDS Research (CFAR), with infrastructure/operations support provided by the Center for the AIDS Programme of Research in South Africa (CAPRISA), the Africa Health Research Institute (AHRI) and the UKZN HIV Pathogenesis Programme (HPP).

More News

Press Releases

Ragon Faculty Study Identifies Novel Immunization Strategy for Broad Influenza Protection

Researchers at the Ragon Institute have developed a novel immunization strategy that shows promise for protecting against both group 1 and group 2 influenza A viruses. The strategy, detailed in their recent study, relies on eliciting a single amino acid change in antibodies to generate broadly neutralizing antibodies (bnAbs).

Press Releases

Ragon Study Finds Key Mechanism of Immune Evasion by SARS-CoV-2

Their findings, to be published in Cell next month, reveal how the virus manipulates immune system processes to avoid destruction by natural killer (NK) cells, a type of white blood cell that is crucial for fighting viral infections.

Press Releases

Ragon faculty sheds light on intricate functions of Resident Tissue Macrophages (RTM’s) which extend beyond immune defense

The lab of the Ragon Institute faculty member Hernandez Moura Silva, PhD, recently published a review in Science Immunology regarding resident tissue macrophages (RTMs), shedding light on their multifaceted roles in organ health.