Ragon Institute of MGH, MIT and Harvard
MIT Department of Biological Engineering
(617) 258 7641
The Bryson lab is working to determine how cells of the immune system control and eliminate one of the world’s most deadly pathogens, Mycobacterium tuberculosis (Mtb).
How Mycobacterium tuberculosis is controlled by humans remains a poorly understood process. To address this knowledge gap, our research group combines approaches in microbiology, immunology, and bioengineering to understand and manipulate the complexity of phagocyte state and function in the lung. Paired with these cellular questions, our group develops novel tools to query and perturb the phagosome which we hypothesize contributes to effective Mtb control.
Dr. Bryson received a BS in Mechanical Engineering and PhD in Biological Engineering from MIT. He pursued postdoctoral training at the Harvard TH Chan School of Public Health with Sarah Fortune, where he became fascinated by the complexity of interactions between Mtb and the host. He joined the MIT faculty in 2018.
Itoh, C. Y. et al.
bioRxiv 2020.09.29.318352 (2020) doi:10.1101/2020.09.29.318352
Hie, B. et al.
Annu. Rev. Biomed. Data Sci. 3, 339–364 (2020)
Peters, J. M., Blainey, P. C. & Bryson, B. D.
bioRxiv 2020.08.06.240424 (2020) doi:10.1101/2020.08.06.240424
Gideon, H. P. et al.
bioRxiv 2020.10.24.352492 (2020) doi:10.1101/2020.10.24.352492
Hie, B., Bryson, B. D. & Berger, B.
Cell Syst. (2020) doi:10.1016/j.cels.2020.09.007
Ma, F. et al.
bioRxiv 2020.12.01.406819 (2020) doi:10.1101/2020.12.01.406819
Bryson, B. D.
mSphere 6, (2021)
Hie, B., Zhong, E. D., Berger, B. & Bryson, B.
Science 371, 284–288 (2021)
Iris Abrahantes Morales
Research Technician I
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